建设内容和目标
协云基因在病原体分析与微生物组学方面具备国际领先的算法开发与应用能力，致力于为用户提供从样本管理，数据管理，数据分析到定制化决策支持的微生物数字化实验室解决方案。
成功案例
国家流感中心流感预测预警平台
国家CDC流感疫苗株预测平台
检测数据管理，分析与知识发现平台
微生物样本资源库与实验室管理系统
微生物NGS数据分析云平台
生物信息学资源管理系统
本团队在微生物领域自主研发的算法十余项，专利3个，PCT专利2个，软著11个，通过与客户进行科研合作发表的论文三十余篇，以下为部分代表性成果展示。
自主算法
Cluster-transition determining sites underlying the antigenic evolution of seasonal influenza viruses. Molecular biology and evolution, 2019.
Generation of a live attenuated influenza vaccine that elicits broad protection in mice and ferrets. Cell host & microbe, 2017.
Evolution-informed forecasting of seasonal influenza A (H3N2). Science Translational Medicine, 2017.
Cell membrane proteins with high N-glycosylation, high expression, and multiple interaction partners are prefered by mammalian viruses as receptors. Bioinformatics 2018
Network of co-mutations in Ebola virus genome predicts the disease lethality. Cell research, 2015.
Sequential reassortments underlie diverse influenza H7N9 genotypes in China. Cell host & microbe, 2013.
客户服务成果
Metagenomic analysis of viral nucleic acid extraction methods in respiratory clinical samples. BMC genomics, 2018.
An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network. Nature communications, 2017.
ICM: a web server for integrated clustering of multi-dimensional biomedical data. Nucleic acids research, 2016.
AAgAtlas 1.0: a human autoantigen database. Nucleic acids research, 2016.
PREDAC-H3: a user-friendly platform for antigenic surveillance of human influenza a (H3N2) virus based on hemagglutinin sequences. Bioinformatics, 2016
Clinical metagenomic analysis of bacterial communities in breast abscesses of granulomatous mastitis. International Journal of Infectious Diseases, 2016.
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